HysterSisters Articles for Hysterectomy
Hyperplasia, Atypia, and Gynecologic (GYN) Cancer
From the GYN Cancer Articles List
SHARING IS CARING
I have been diagnosed with hyperplasia with atypia. Is this cancer or not?
Endometrial hyperplasia is an abnormal overgrowth of the endometrium (lining of the uterus) resulting from prolonged stimulation by estrogen without the proper changes in progesterone levels to trigger regular menstrual bleeding. This causes the endometrium to thicken and become glandular. This is hyperplasia, which may also be a premalignant lesion. In other words: it is not cancer, but it may be a precancerous condition. In about one in four cases, these lesions do become cancerous, so it is certainly something to take seriously.
There are four types of endometrial hyperplasia, some more concerning than others.
Hyperplasia can be either simple or complex. Simple hyperplasia usually refers to the buildup of extra cells in the endometrium without other changes in the structure of the uterine lining. Complex, or glandular, hyperplasia includes both a buildup of cells and the formation of glandular tissue. Women are more susceptible to both forms of hyperplasia during perimenopause, the years just prior to menopause, when menstruation becomes irregular. Post-menopausal women on hormone replacement therapy also have an increased risk for developing hyperplasia.
Atypia refers to the presence of abnormal, possibly precancerous cells in your biopsy. The presence of atypia increases the chance that hyperplasia will develop into malignant tumors.
Simple and complex hyperplasia without atypia together carry just a 3% risk of developing into endometrial cancer. This is about the same risk as a woman without hyperplasia, so hyperplasia without atypia is not considered a precancerous condition. Most gynecologists will recommend treating these conditions with progestin therapy to trigger the sloughing off of the endometrial lining as occurs during regular menstruation.
Hyperplasia with atypia, however, is considered precancerous. The presence of atypical cells means that you and your doctor will want to treat your hyperplasia more aggressively and keep a careful eye on its development. Simple hyperplasia with atypia can be treated with progestin therapy and has a less than 10% chance of developing into cancer. Complex hyperplasia with atypia, though, carries a 25–30% chance of developing into cancer, and in some cases preexisting cancerous cells are detected during treatment. The more advanced and severe the atypia is, the more likely it is to develop into cancer. Many gynecologists will recommend hysterectomy for complex hyperplasia with atypia.
Consult with your doctor and seek a second opinion
if you are unsure about the path he or she is recommending.
This content was written by staff of HysterSisters.com by non-medical professionals based on discussions, resources and input from other patients for the purpose of patient-to-patient support.
SHARING IS CARING
HysterSisters Free Hysterectomy BookletWhat 250,000 Women Know About Hysterectomy
with 50 pages of information, helpful tips and hints as you prepare and recover from hysterectomy through an organized timeline.
Options to Hysterectomy
Hormone and Menopause
Intimacy after Hysterectomy
Fitness after Hysterectomy
Grief and Loss
Ask A Doctor
Do you have a question?
If you have a medical support question related to this article, come JOIN US in our HysterSisters Community Forums. You will receive helpful replies to your questions from our members. See you there!
Recommended for Hysterectomy Recovery
The HysterSisters Store has gathered products made specifically for your recovery from surgery. Here are the best sellers we can recommend to help you:
- The Great Binder Set - We have made it very easy for you and combined the two best binders and the Silky Sac into a great set to save you money! Our favorite is the Perfect Pocket binder with cold/hot packs!
- Deluxe Hyst Prep Set - As you plan, we've gathered the best products into one set for special pricing.
- Post-Op Panty - These great panties speed recovery, and reduces scarring. They contain a medical-grade silicone panel over incision to reduce scar's apperance while they provide support to weakened muscles and tissues from surgery. Excellent!
- Softest Bra Ever - When you want to wear something, but feel nothing. This is the softest bra ever, in microfiber with no hardware or tags to chafe or dig! The comfort-ribbed underband stays in place gently, so it is perfect for sleeping and lounging.
- HysterSisters Accessory Kit - Are you a HysterSisters fan? This set has a fun collection of HysterSisters items.
- Very Private Moisture - Once your doctor gives you the green light for intimacy, this is the stuff! This is a best selling product with a high rate of permanent, satisfied, repeat customers! Relieves vaginal dryness instantly, protects tissue & enhances intimacy.
"Buy it for the problem, use it for the pleasure."
Find a Surgeon
|Lori Warren, M.D.
3900 Kresge Way
Louisville KY 40207
|Antonio Gargiulo, M.D.
Brigham and Women's Hospital
75 Francis Street
Boston MA 02115
|James Greenberg, M.D.
1153 Centre Street #36
Jamaica Plain MA 02130
|John Miklos, M.D.
3400 Old Milton Parkway
Bldg. C, Suite 330
Alpharetta GA 30005
|Tiffany Jackson, M.D.
601 Clara Barton, Suite 160
Garland TX 75042
|Katherine Hsiao, M.D.
3905 Sacramento Street, Suite 204
San Francisco CA 94118
|Stephen Zweibach, M.D.
815 S Parsons Ave
Brandon FL 33511
|David Zisow, M.D.
2005 Rock Spring Rd Ste. 3
Forest Hill - Baltimore MD 21050
|Megan Daw, M.D.
Western Carolina Women's Specialty Center
2100 Ridgefield Blvd
Asheville NC 28806