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Any stats on PMDD cure with ovary removal? Any stats on PMDD cure with ovary removal?

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Unread 01-23-2011, 08:25 PM
Any stats on PMDD cure with ovary removal?

Any stats on PMDD cure with ovary removal? And how about leaving the uterus in? I know it's usually not done that way, but if it's not broken...
From what I've read, ovary removal will cure the PMDD in most all cases. Is that right?
Thanks for the info!
Destiny Driven!
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Unread 01-24-2011, 05:11 AM
Re: relief from the pmdd after having your ovaries removed?

From what I understand of PMDD, the removal of the ovaries is a definite cure for PMDD. The consideration most of us have is whether the loss of hormones will give us a different set of problems.
I know people who have just had the ovaries removed to cure PMDD, and have left uterus in. Mostly this was done to cut down on recovery time after surgery. For me it wouldn't have made sense as I got a lot of pain from uterus and keeping it without ovaries woud have been mad!

The other thought is that HRT is much trickier if you have a uterus. For most of us it is the progesterone part of the cycle that is the problem, and if you are on HRT and you have a uterus, you need to have some progesterone to protect the uterus. I seem to be intolerant of most progesterones (synthetic or otherwise) and they made my PMDD symptoms come back, so removing the need for any progesterone is definitely a plus point for me.

I am only 2 weeks post op but looking forward to a PMDD free life. I don't want to ever be as depressed as I got before my period and I worry that the estrogen drop will bring depression with it, but I am on ERT and hoping that I won't.

Hope this helps x
Unread 01-24-2011, 09:37 AM
Re: relief from the pmdd after having your ovaries removed?

WOW!! I am truly impressed! Thanks for answering! (People do answer these!!)
I didn't know realize you were so close post-op. How are you feeling?
I KNOW that progesterone is what my body hates! I think it is allergic to it! Really! I dunno about natural progesterone (In case I leave the uterus in); I tried it once and it just made me feel lethargic, heavy, weight-ey, if that makes sense. Even on the pill, I feel so "pumped up" hormonally. And the hunger on the pill is like pre-period, just all the time.
I am looking forward to having my ovaries removed. If you don't mind, I'd like to keep in touch as I am beginning the "serious" phase of ovary removal...tho something have thought about for a long time (years). Thanks again for the reply and ANY info is appreciated!
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Unread 01-25-2011, 11:09 AM
Re: Any stats on PMDD cure with ovary removal?

You're welcome DestinyDriven! I have been on a horrible journey the last 15 months and if what I have learned helps someone else that kinda makes it feel better!!

My trouble really worsened when I had an ovary removed coz of a dermoid cyst. My gyno thinks they took out my dominant ovary and my remaining ovary was a bit slow to "take up the slack". I know they say PMDD gets worse with age as your estrogen levels drop, and I guess I was just pushed down that path a bit quick coz of the surgery.

I started estrogen therapy and that really helped, but I was struggling with the pain and it was clear I needed a hyster. The question was just whether to get shot of last ovary or not - and boy did I struggle with that decision! The PMDD specialist I had seen was adamant I should have ovary out but I had to travel to see him and i wanted surgery locally. To start with my local gyno recommended keeping ovary coz of my age (34), but he changed his mind and said to "go for it and get your life back". So I decided to go with his advice.

As it happens, along with the uterus problem they found endometriosis and several small growths on the ovary - he says this reinforces that it was the right choice to remove it which is nice to know.

I am so glad I had the opportunity to try estrogen before surgery, and I used testosterone for a while too so I knew what that was like. I know it is very different being on HRT with your own hormones but any experience is kinda reassuring. I don't know what treatment you have tried for PMDD but it might be worth looking at estrogen therapy even if it is just an interim step before surgery?

The other thing I would say is that you really need to have a gyno you can trust. My local gyno isn't a PMDD specialist but in some ways that helped when it came to make the decision because I knew he had experience of all sorts of people. He's a decent guy and isn't one of the gynos that think PMDD is a minor inconvenience. He really does seem to get that it ruins your life.
I had quite a rough time after surgery with internal bleeding. I had transfusions but my blood count is still way down and I get very tired easily. My gyno came and saw me every evening until I was discharged and has been brilliant. He says I may have to tweak the HRT to get it right but I trust him to guide me through that.
I have had a few moments when I get a little bit sad and down, but from what I read on here that is common post surgery and I guess low blood count is not going to help. I worry so much about getting as depressed as I was before and I think it is just going to take time for me to put it all in the past.

Sorry this is turning into mammoth reply! Please do keep in touch it would be good to know your progress. Best wishes to you x
Unread 01-25-2011, 08:07 PM
Re: Any stats on PMDD cure with ovary removal?

Thanks so much for the info. I have tried everything! Believe me. And I am 44, soon to be 45 and I can tell "things" are getting worse. I think back and just know now that I has abnormal periods since day 1. I wouldn't be able to sleep, huge clots, etc. until I "happened upon the pill" (thinking back~what a life saver!) and was on that for many years. Now I just can not tolerate any deviation in hormones. The off week has turned into the off 5 day regimen, which turned into being off the pill for 3 days and now it's being off the pill just three days every 3 months. But I just don't feel "optimal". I feel bloated and weighty and my hair cannot stand the progesterone and it is thin and thinner. I think back and it all makes sense: How WONDERFUL I felt being pregnant, (Except for the last 2 monts). It's like my body is allergic to progesterone and during my period (when off the pill) it just totally flushes everything out. I wonder if it really is possible to have an allergy-type response to progesterone? Anyway, I have a good OB/GYN but she did not want to just remove my ovaries. I get a second opinion on the 14 of Feb. I figure if it ain't broke, keep it in. I mean, yes, if I need estrogen, then it could be an issue. But maybe I won't need estrogen and then I could have left all other parts in. I read where someone said that no one ever got PMS from going through menopause~ I had to chuckle because I believe I have that same fear "What if I am worse off with PMS after the surgery?" I am so thankful for this site, and for connecting with someone who has gone through it!
BTW~I am new here and still learning how to navigate through...any tips?
Unread 03-19-2011, 08:18 PM
Re: Any stats on PMDD cure with ovary removal?

Hello! I am also considering a hyst for PMDD. How is your recovery going now? Any response is greatly appreciated! Thank you!
Unread 03-22-2011, 11:02 AM
Re: Any stats on PMDD cure with ovary removal?

Hi there Newinark

I'm 10 weeks post op now and doing quite well. I have had to change my hormone dosage since the op as hot flashes started getting bothersome and I started getting quite depressed. I find any fluctuation in hormones a bit of an ordeal to be honest so it hasn't been the smoothest of rides so far. Having said that, it is nice not to have my own cycle as I constantly felt I was chasing it - if that makes sense! I don't feel at my best yet, but then I know I am a long way off feeling at my worst too.
I would do it all again that's for sure - but I would be lying if I said there hadn't been a few ups and downs so far.
Good luck with your decision
Unread 03-22-2011, 02:05 PM
Re: Any stats on PMDD cure with ovary removal?

THANK YOU SO MUCH for your response!!! Please keep me posted, if you don't mind. I wish you a speedy recovery and more awesome days!
Unread 03-22-2011, 02:43 PM
Re: relief from the pmdd after having your ovaries removed?

From what I understand of PMDD, the removal of the ovaries is a definite cure for PMDD.
Actually, this isn't exactly true. Hormones may only be part of the picture. There is some research that indicates that the problem may actually be with serotonin deficiency and/or the interaction of hormones with the neurotransmitters. Thus, removing the ovaries and providing steady HRT still may not correct the serotonin or interaction issue.

The selective serotonin reuptake inhibitor class of antidepressants are effective for some women for PMDD so that is an avenue to explore as well before having a BSO.

Here are a couple links that might be helpful on PMDD in general:

Unread 03-22-2011, 04:07 PM
Re: Any stats on PMDD cure with ovary removal?

Thanks for that Weiser, that is interesting about the serotonin - I know a few people who have done well on antidepressants for PMDD.
The PMDD specialist I was under said the only sure cure was ovary removal or menopause.
For me it was very clear that the cycle problems I had only occurred once I had ovulated, and during the progesterone phase of the cycle, and I had good results from suppressing my cycle. Had I not, I think antidepressants would have been a logical step for me to try, but I was encouraged to try a hormonal solution first.

It is a major decision - I know coz I found it a very hard one! and I am very grateful I had the chance to try hormone treatments and see how I responded. There is no doubt that having the physical problems I had made my decision easier. It is certainly worth exploring every available option as we are all so different.

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