You need to ask your doctor about alternatives ways to take oral estrogen pills. The dose orally is much higher because so much of it is lost during the digestive process. If you were to use a whole pill sublingually, for example, you would be getting too high a dose.
I know there are members who use the generic estradiol instead of Estrace pills. It's worth a try to see if they're right for you. It's one of the low-cost drugs available at pharmacies--even without prescription insurance.
Many women do just fine on the generic, and some do not. The only way to find out is to try it. Trying the brand first is a good idea so you can compare the effect you get from each one; do stay on each one at least several weeks before switching, though, to give your body time to acclimate to it.
Also, pay attention to which manufacturer's generic you are given when you first decide to try the generic; they each may use different fillers and binders, and it's these "inactive ingredients" that some women find affect the results they get from the estrogen in the tablets.
The requirement for generics is that the blood levels achieved from a particular dose need to be within +/- 20% of the levels achieved with the same dose of the brand name product. They *may* be a lot closer but it's not required, and that's another reason some women find that they work differently.
Are the generic estradiol tablets the same as estrace tablets. I was going to get estrace, but then saw estradiol tablets are available and are much less expensive.
Also, if I want systemic absorption, (blood level increase), and at the same time bypass the liver, should I take the tablets vaginally or dissolve them under my tougue?
Thanks as always!
I take the estradiol tablets and am doing fine on them. It is also a great money savings. My dr also has me on the vagifem suppositories twice a week and that helps a lot with the vaginal symptoms. I don't know how much the localized tablets work systemically.