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Abnormal Pap tests after hysterectomy Abnormal Pap tests after hysterectomy

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Unread 05-14-2012, 03:05 PM
Abnormal Pap tests after hysterectomy

I have had abnormal paper tests ever since I had my full hystgerectomy in 2006. I finally got up the nerve to ask my doctor if it was HPV and it is. She has done laser surgery, Colposcopy, scrapings, etc. I have had it all. Now the doctor is trying a vaginal cream therapy. It is a cream that is normally used for Topical Skin Cancer. Efudex 5%. I am really nervous since it is not intended to be used vaginally has anyone else out there heard of this treatment. You give yourself the medicine once a week for 10 weeks. then I will go in and be checked at the 4 week or half way mark and then have a pap test again after the 10 weeks. Then she wants to use topical Premerian for 4-6 weeks. I am just wondering if there are good results from this type of therapy or if anyone has ever heard of this treatment
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Unread 05-14-2012, 07:17 PM
Re: Abnormal Pap tests after hysterectomy

I'm so sorry that you are going through this. Especially after a hysterectomy that you hope will be the only treatment needed to squash the HPV. I don't have any experience with the cream that you mention, but I hope it works out or you with no side effects. Good luck.
Unread 05-14-2012, 07:41 PM
Re: Abnormal Pap tests after hysterectomy

Thank you so much for your thoughts and concern. I really do wish that there is someone out there that might have knowledge or experience with this vaginal cream
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Unread 05-17-2012, 10:07 PM
Re: Abnormal Pap tests after hysterectomy

Hi there,

I am starting into this VaIN/hpv journey. I had severe cervical dysplasia over 11 years ago. Had 2 cone biopsies that seemed to clear it up. I was HPV negative/normal paps for 11yrs. Had hyster for other reasons in Jan 2009. Normal paps continued until last spring. I am seeing a gyn onc now, and he says it is very low grade at present, trying to see if it clears. In June, I will have yet another colposcopy, and he will do biopsies at that time. And another pap. If still abnormal, he wants to start me on Aldara cream, another type of cream used for this issue. I will find out more in June.

I would love to hear how your treatment goes. PM me or post here, and BEST of LUCK!!! Search Efudex on this site... I'm sure there are others who have tried this..

Unread 05-22-2012, 01:50 PM
Re: Abnormal Pap tests after hysterectomy

Is your doctor a gyn/onc? I have been treated for vaginal dysplasia and do know some information about the 5-FU.
Unread 05-24-2012, 08:53 AM
Re: Abnormal Pap tests after hysterectomy

Yes she is Gyno. What do you know about the use of this cream as a mediation for my dysplasia
Unread 05-24-2012, 06:58 PM
Re: Abnormal Pap tests after hysterectomy

Sorry I did not reply more earlier, but it had been a few days since your last post before I actually replied, and I wanted to be sure you were still around and still wanted the information.

First, a gyno is not the same thing as a gyn/oncologist. If you are not seeing a gyn/oncologist, please ask for a referral to see one. You deserve the best care you can get and gyn/onc's are the specialists in this area. While cervical dysplasia is quite common and gyn's treat it all the time, vaginal dysplasia is much less common. So you really want someone providing care who sees this frequently and is current with the most updated surgical and treatment techniques. Please go see one.

Do you know the extent of your vaginal dysplasia (VaIN 1 or 2 or 3)? Is it at the cuff or on the wall?

I have talked to several women who used the Efudex cream. Yes, 10 treatments is the commonly prescribed course. One woman I knew made it through 7 treatments. The others made it through 3 or 4. It can apparently be quite uncomfortable as the skin is eroding away.

I have had surgical excision and laser and also treatment with imiquimod. My gyn/onc did not recommend the 5FU, citing discomfort. I did ok with the imiquimod--I got through the whole course of treatment. It was uncomfortable at times, but manageable.

This can be a really frustrating disease to deal with. Hang in there! Let us know if we can answer additional questions or if you just need someone to bounce ideas off of. Please let us know how you are getting along.


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