I have been taking Vitamin E and Evening Primrose for hot flashes and other menopause symptoms for one year since my TAH/BSO and I must admit that the hot flashes are less often and less severe ( I'm not sure if it is the supplements or just time). I can't take HRT because of a blood clotting problem. I started on Fosamax as I lost 11% of my bone mass in 1 1/2 years, so ladies do ask you Dr. for an annual bone scan to moniter this. I saw my cardiologist this week and he told me to stop the Vitamin E as it interferes with my Zocor to lower my cholesterol. Thought I would pass that on to everyone. Always check with your Dr before taking supplements and remind him or her when you see them so you don't have any interactions etc.