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DES and Vaginal Adenosis

From the GYN Genetics Articles List

 DES and Vaginal AdenosisI am a DES daughter with vaginal adenosis. What can you tell me about this condition?


Vaginal adenosis is a nonmalignant abnormality that can be found in up to 90% of women who were exposed to DES (diethlstibestrol) in the womb, especially prior to the eighth week of gestation.

The affected vagina can contain glandular, or mucus secreting, tissue rather than being epithelialized with squamous epithelium. As a result, abnormally heavy vaginal discharge can occur. Because heavy vaginal discharge can also indicate infection, it is important that you work with a medical professional to be sure the issue is vaginal adenosis. While an infection would require treatment, vaginal adenosis may only require close monitoring by your medical professional.

As you age, changes in the vagina can cause the discharge to lessen and even stop as the vagina and cervix become epithelialized. If the discharge continues into menopause, however, it could indicate adenocarcinoma.

Vaginal adenosis is associated with a high risk of vaginal carcinoma. Thus, if you are a DES daughter with vaginal adenosis, you will need to work closely with knowledgeable physicians to attempt to minimize the risks of cancer developing. You should also eat well, exercise regularly, manage stress, and get plenty of rest to keep your body as healthy as possible. In addition, avoiding alcohol, tobacco, recreational drugs, and unsafe sex could help keep your vagina healthy.


This content was written by staff of HysterSisters.com by non-medical professionals based on discussions, resources and input from other patients for the purpose of patient-to-patient support.

09-14-2013 - 06:05 PM


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