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Mood Swings after Hysterectomy

From the Hysterectomy Recovery Articles List

Mood Swings after HysterectomyI've been having horrible mood swings since my hysterectomy. Is this normal?


The simple answer is yes, it's normal. Many women express their frustration with inexplicable mood swings after their hysterectomy. As for the cause of such mood swings, there are several different possibilities.

First of all, the combination of medication, anesthesia, a lack of sleep, and other surgery-related issues can make anyone moody. Post-op moodiness is not exclusively reserved for hysterectomies, so don't panic if you wake up grumpier than normal.

There are, however, some special considerations when it comes to a hysterectomy. In general, you have to realize that your body just underwent a major surgery that can vastly affect your hormone levels. Whether you kept your ovaries or not, whether you started hormone replacement therapy (HRT) immediately or not, your body is in some amount of shock.

If you had your ovaries removed and did not go on hormone therapy right away, your body could be adjusting to the sudden decrease in estrogen production. This shock can create menopause-like symptoms, which would include mood swings. If you did start on hormones right away, it may still take some time for your body to adjust to the changes.

If you kept your ovaries, there is still a chance that their blood supply was disrupted at some point during surgery, causing some menopausal symptoms post-op. These symptoms should fade away as the ovaries resume normal functioning again. Additionally, because you still have your ovaries, you may still have PMS and its symptoms without the bleeding and uterine cramps, of course. If you had mood swings during PMS before, you may continue to have them after your hysterectomy.

If several weeks have passed and you are seeing no improvements in your symptoms, be sure to let your doctor know. Post-op medications (especially HRT) require a lot of trial and error, so it may be that you need to try a new dosage. You'll also need to consider any other medications you are taking. HysterSisters on thyroid medications or antidepressants have run into problems combining these with HRT.


This content was written by staff of HysterSisters.com by non-medical professionals based on discussions, resources and input from other patients for the purpose of patient-to-patient support.

10-23-2013 - 06:59 PM


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