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Uterine Choriocarcinoma

From the GYN Cancer Articles List

What is uterine choriocarcinoma?What is uterine choriocarcinoma?


Uterine choriocarcinoma is an uncommon, malignant form of gestational trophobalastic disease (GTD). GTD is a group of tumors that start in the tissue that would normally become the placenta during a pregnancy. Though uterine choriocarcinoma is very aggressive and much more likely to grow quickly and spread to other organs, it is usually curable and has a good prognosis.

According to the American Cancer Society, only 2–7 of every 100,000 pregnancies in the United States will be affected by uterine choriocarcinoma, and according to the National Health Services (NHS) Specialised Services, only 1 in every 50,000 births will be affected in the United Kingdom.

Usually, this cancer will occur within one year of a pregnancy. Half of all uterine choriocarcinomas are believed to begin as a complete molar pregnancy (an abnormality of the placenta another type of GTD). Approximately 25% of them develop following a miscarriage, abortion, or tubal pregnancy. The remaining 25% percent may develop following a normal pregnancy; this type of uterine choriocarcinoma tends to be the most aggressive.

When determining treatment options, it is critical to determine right away if the cancer has spread and decide if you wish preserve your fertility. This type of cancer tends to respond well to chemotherapy. If the cancer has not spread, chemo may be all that is recommended for treatment.

Depending on fertility concerns, your age, and symptoms, your surgeon may also recommend removing the tumor or your complete uterus. For later stages of cancer that have spread, a different combination of chemotherapy, more surgery, and/or radiation may be recommended depending on the specifics of the tumor and where it has spread. In general, the cure rate for uterine choriocarcinoma is 90% or higher when the cancer has not spread. If it has spread to other organs, prognosis can depend on which additional organs have been affected. Recurrence of uterine choricarcinoma can occur within months or up to three years later.

If you have been diagnosed with uterine choriocarcinoma, working with a knowledgeable gynecologic oncologist could help you determine the best treatment plan for you. Seeking a second opinion could help confirm your choice or open the door to other options.


This content was written by staff of HysterSisters.com by non-medical professionals based on discussions, resources and input from other patients for the purpose of patient-to-patient support.

03-11-2014 - 08:46 PM


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