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Gestational Trophoblastic Disease (GTD) Staging

From the GYN Cancer Articles List

GTD StagingHow is gestational trophoblastic disease staged?

All instances of gestational trophoblastic disease (GTD) require treatment. While most cases are benign, there are times when it is malignant. Prognosis and staging when there is cancer can help determine which treatment options are best for you and your situation.

In general, staging is very simple:

Stage I – The cancer is contained within the uterus.
Stage II – The cancer has spread from the uterus but is limited to other pelvic structures.
Stage III – The cancer has spread to the lungs.
Stage IV – The cancer has spread to other organs.

Besides staging, other factors are taken into consideration to help create a score for prognosis:
  • Age
  • Term length/cause of end of pregnancy
  • Months since pregnancy
  • Pretreatment hCG levels
  • Largest tumor size
  • Where it spread
  • How much it spread
  • Previous failed chemotherapy

All of the scores for these factors are added together to make up your score. The higher your score is, the greater your risk. Generally, however, you are consider at risk if you score 7 or higher.

Using both the score and stage helps your physician determine which treatment options would be best for you. Treatments can include surgery, chemotherapy, and/or radiation. For low-risk gestational trophoblastic disease (GTD), the cure rate is nearly 100%. For high-risk GTD, the cure rate is still 80% to 90%, though more invasive treatment may be necessary.

Prognosis for metastatic gestrational trophoblastic disease is good if the following factors are true:
  • Less than 4 months since last pregnancy.
  • hCG level is low.
  • There are no cancer cells in the liver or brain.
  • Chemotherapy has not been used in the past.

Prognosis for metastatic gestational trophoblatic disease is poor if the following factors are true:
  • More than 4 months since the last pregnancy.
  • hCG level is high.
  • There are cancer cells in the liver or brain.
  • Chemotherapy was used in the past.
  • The tumor followed a normal pregnancy.

This content was written by staff of HysterSisters.com by non-medical professionals based on discussions, resources and input from other patients for the purpose of patient-to-patient support.

03-20-2014 - 09:43 PM


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