Premarin cream, anyone??? | HysterSisters
HysterSisters Hysterectomy Support and Information
Advertising Info HysterSisters Hysterectomy Support Tutorial

Go Back   Hysterectomy HysterSisters > Hysterectomy Support Posts > Hysterectomy Recovery (post hysterectomy) is a massive online community with over 475,000 members and over 5 million posts.

Our community is filled with women who have been through the Hysterectomy experience providing both advice and support from our active members and moderators. is located at 111 Peter St, Toronto, Canada, M5V2H1 and is part of the VerticalScope network of websites.

With free registration, you can ask and answer questions in our HYSTERECTOMY forum community, get our FREE BOOKLET, access Hysterectomy Checkpoints and more.

You are not alone. The HysterSisters are here for you. Join us today!
join HysterSisters for hysterectomy resources and support

Premarin cream, anyone??? Premarin cream, anyone???

Thread Tools
Unread 05-14-2003, 12:53 PM
Has Anyone Used Premarin Cream?


Went to the doc today (4 weeks post-op) and he prescribed Premarin vaginal cream. He told me that it would help with the healing process and elasticity in the vagina. I'm 37 and have my ovaries.

Of course when I got home and read the accompanying information pamphlet, all those risks and side-effects have me wondering about it!

Can anyone tell me of their experience with this cream? Any negative side-effects? In your experience (or opinion), do the benefits outweigh the risks?

I didn't post this in the hormone jungle because I noticed that it says "Surgical Menopause" on the logo, and I still have my ovaries...? Hope I'm posting in the right place.

Thanks ladies!
p.s. I did do a hasty search on this, but all the posts were talking about the Premarin patch or oral meds???
Sponsored Links
Unread 05-14-2003, 08:25 PM
Premarin cream, anyone???

figured I'd try again, later in the day!
Unread 05-14-2003, 08:39 PM
Premarin cream, anyone???

I started Premarin cream at 6 week post op. My doctor instructed me to use it topically so I pitched the applicator dealy that was in the packet. I have already noticed a difference in dryness and elasticity. Haven't had any negative reaction to the stuff yet.

Went to see Bowling for Columbine last night in Boulder. They talk a lot about fear manipulation by the media etc. So I know they have to put the warnings on medicines etc but they don't put any information about the percentage of people that have problems. I think those "warnings" are more to keep the drug company out of court than anything else. Read the warnings on a bottle of aspirin and you wonder why it's even legal.

I guess as long as I breathe polluted air and eat processed food and drive a car every day I am "at risk" anyway!

Try it and see if it works. If not, don't use it. Good luck.
Sponsored Links
Unread 05-14-2003, 09:05 PM
Thanks Becky...

...I'm sure you're right about all those warnings, in this lawsuit-dominated society.

Thanks...I appreciate your reply!

I haven't had any dryness issues at this point (of course I'm not even close to getting the OK for sex yet), but after my doc took a peek today, he said it'll help with my healing, so I'm all for it! I'll take all the help I can get!

take care.
Unread 05-15-2003, 01:35 PM
Premarin cream, anyone???

Hi Marianne,

The amount that would go through your system is probably so minute, I wouldn't think it could cause any problems. I am on HRT, and I sometimes supplement with Premarin cream (as I am on a low dose estrogen and sometimes get vaginal dryness). They put warnings on everything, including the coffee you get at McDonalds! However, it is a good habit to read the warnings and drug interactions on every medication you take. Good luck, hope it helps you.


Unread 05-21-2003, 10:06 AM
Premarin cream, anyone???

I was also put on Premarin Cream at 5 week check-up. I was told it would help with elasticity, clear up dis-charge and vaginal itching. I have had no bad side effects form this medication and it has helped greatly w/ itching.
Unread 05-21-2003, 11:55 AM
Premarin cream, anyone???

Hi! I am six weeks post op after a LAVH TVH/BSO and have been on Premarin/Prometrium for three years for perimenopause symptoms. Now that my ovaries are gone for good (HOORAY!) I am looking for a safer alternative to the above mentioned drugs and have read some compelling advice on Natural Hormone Replacement from a few good sources. They aren't suggesting plant based photoestrogens (which usually aren't strong enough) but bioidentical hormones produced in a compounding pharmacy and by prescription only from an MD.
They make a whole lot more sense if we are planning to stay on these things for the health benefits for a number of years. My main concern is osteoporosis as I have a strong family history and am a 30 yr smoker.
But I digress-- there are bioidentical creams as well as pills. And the creams are a more direct delivery system hence lower doses needed and less impact on the liver.
All ingredients are USP approved and are regulated like Rx meds. There is however little research done as none of them are patentable (because they duplicate nature exactly).
I would suggest reading Wisdom of Menopause by Christiane Northrup MD (a wonderful book even if you aren't concerned about HRT) and maybe Natural Hormone Replacement by Jonathan V. Wright, MD and John Morgenthaler. They were recommended by my MD sister-in-law, who is on bioidentical HRT amd very pleased with it.
I am not willing to just accept the standard Rx the drug companies have a bazillion warnings on and are pretty far from being anywhere near our natural hormones in composition. Mare's urine (from which Premarin is derived) only has two of the three components of human estrogen, for example.
So check it out. We have choices, and even in this berg (Asheville, NC) we have a compounding pharmacy. You can find them online as well.
Good Luck!--Joanne
Unread 05-21-2003, 04:42 PM
Premarin cream, anyone???

The negative publicity with Premarin is well founded as Premarin type preparations (pills and creams) are NOT human identical estrogens, ladies. Premarin compounds stay in the body and will target breast tissue and the danger in the Premarins are that they stay in your body TOO long and that is what they think causes the breast cancer thing.

The natural hormones, the bioidenticals (those which are as identical as those made by your own body - and Premarin is NOT identical) are the ones I have sought out and found. I take estradiol patch (Vivelle) and use a Progestrone (yam or soy based) 3% cream to balance the estradiol. If you do not balance the estradiol with progesterone, receptors for progesterone are targeted by estrodiol, which is not normal. Balance and bioidentical is the key to safety with HRT.

I researched the issues at extreme length before my surgery 6 days ago and am very pleased that I did. My compounding pharmacists is excellent, he knows his stuff and is current on his information.

My doc (who is an older ob) did not order Progesterone, but the compounding pharmacists said for me to insist on it. My compounder is a chemist, and should know is how I think of it. I researched him, too; as I am also professionally interested in endocrinology (hormone science).

The pharm also says the estradiol does not stay in your system too long that is why it is safer to use. In addition, he says that if you get the closest balance you can to the right hormones for you weight gain will be less of an issue because the female hormones are so closely tied with insulin and thyroid hormones any imbalance will cause a large number of medical issues eventually.

The post before this one was good advice, agree with her post.

The importance of your HORMONES cannot be overstated. The sex hormones are just as important as INSULIN, THYROID - ALL of them. Matching them as closely as possible is good medicine and body chemistry.
Unread 05-21-2003, 04:47 PM
Premarin cream, anyone???

Another problem with Premarin tablets is that it must go through your liver first. This means the liver will clear alot of the dose first, then it goes in your bloodstream. The dose of oral Premarin is high, so that the liver takes out it's share and then the rest goes to your hormone receptors.

Creams and patches do not go straight to the liver, but to your receptors first. Not as much reaches the liver.

It just doesn't make sense to take double the amount, just to have the liver remove it - it is WORK for the liver to remove the Premarin compounds.....another reason I chose patch/topical application.

Our Free Booklet
What 350,000 Women Know About Hysterectomy: Information, helpful hints as you prepare and recover from hysterectomy.
Answers to your questions

Thread Tools

Forum Jump

Similar Threads
From This Forum From Other Forums
2 Replies, Last Reply 10-31-2008, Started By Caribi
19 Replies, Last Reply 07-10-2008, Started By janny108
19 Replies, Last Reply 04-07-2008, Started By DeniseS
2 Replies, Last Reply 01-08-2008, Started By java jane
2 Replies, Last Reply 04-06-2006, Started By Haley2005
2 Replies, Last Reply 06-11-2005, Started By CyberDeez
4 Replies, Last Reply 04-10-2005, Started By heather_mi74
2 Replies, Last Reply 02-24-2004, Started By VDVinx
1 Reply, Last Reply 10-20-2003, Started By AndreaInNY
3 Replies, Last Reply 10-02-2003, Started By lja14
0 Reply, Natural Meno Post Hysterectomy - Kept Ovaries
2 Replies, Natural Meno Post Hysterectomy - Kept Ovaries
6 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
2 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
4 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
2 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
3 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
1 Reply, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
4 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause
6 Replies, No Uterus - No Ovaries - Yes HRT - Surgical Menopause


Hysterectomy News

December 4,2020


HysterSisters Takes On Partner To Manage Continued Growth And Longevity
I have news that is wonderful and exciting! This week’s migration wasn’t a typical migration - from one set ... News Archive


Calendar - Hysterectomies - Birthdays

Request Information

I am a HysterSister


Featured Story - All Stories - Share Yours


Your Hysterectomy Date

CUSTOMIZE Your Browsing  

$vbulletin->featuredvideos is not an array!