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Anybody using estrogen after cancer diagnosis? Anybody using estrogen after cancer diagnosis?

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Unread 02-23-2004, 07:24 AM
Anybody using estrogen after cancer diagnosis?

When I had my hyst 2 years ago, my gyn onc had no problems prescribing a hefty dose of estrogen for me. As more research on the risks and benefits of estrogen came out, he asked my to reduce and eventually discontinue the estrogen.

His reasoning, which my medical oncologist also agrees with, is that people who get one cancer, tend to get others, so even if the current cancer is not estrogen influenced, why take the chance, given that the benefits of estrogen (other than relief of hot flashes and symptoms of menopause) are less than what was thought.

Like Linda, I find that premarin cream applied locally to my vagina and urethral tissues, keeps my symptoms under control.

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Unread 02-23-2004, 07:42 AM
Anybody using estrogen after cancer diagnosis?

Hi everybody,
Thank you so much for all the replies. This is such a wonderful site. It looks like the doctors are split when it comes to hrt or ert use after cancer diagnosis. My doctor suggested estring and I am afraid to use it. I started using 1%estriol compounded cream two years after surgery but started having itching problems with it after 3months. I am so tempted to get the prescription filled and use the estring.
MoeKay, if you don't mind, how old are you? Did you take vit E capsules orally or used them vaginally?
Unread 02-23-2004, 09:00 AM
Anybody using estrogen after cancer diagnosis?

Hi Yellowrose
My onc/gyn encouraged the use of hrt right after my surgery for a stage1a, grade 2 endometrial ca at the age of 43. He said with the low stage that there was no reason not to use it. However, my reg. gyn said she would prefer that I wait for two years to use an oral hrt. She did prescribe the Estring, which I have been using for several months. I really like it. She assured me that the vaginal tissues would use everything the Estring had and that it would not go systamatic. I can tell you that the dryness I was experiencing and urinary tract problems have all resolved. She has also suggested that I start using an estrogen cream a couple of times a week. I will be two years post op in July. My onc/gyn was very upset with me for opting not to use the hrt....He said that the latest research says that the benefits far outweigh the risks....I decided that I would go with caution and wait the two years and then decide whether or not to use the hrt. What stage and grade was your ca? I know this is a difficult decision.
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Unread 02-23-2004, 01:17 PM
Anybody using estrogen after cancer diagnosis?

Hi Chris5,
Thank you for the info. I am 2 and half years post op and my cancer was grade 2. I am not sure about the stage whether it is stage 2 or 3. The uterine walls were not invaded but a couple of lymph nodes came positive. I underwent D & C along with hysteroscopy a month before my TAH. There was no sign of cancer in my uterus and ovaries at the time of surgery. Only the lymph nodes were positive. I did not take any form of hrt for the first two years post op though my gyn/onc was encouraging me to use Ert and tried estriol vaginal cream only in the last six months.
Why does your gyn want you to use vaginal cream in addition to the estring? Yes, it is a difficult decision. I am glad I found out this site and thankful for the support of all the hystersisters.
Unread 02-23-2004, 01:49 PM
Anybody using estrogen after cancer diagnosis?

Hi, Yellow Rose--

To answer your questions, I am 56 now and was diagnosed at 51. I applied a 400 IU capsule of Vitamin E vaginally. I do, however, also take 400 IU of Vitamin E orally daily (along with a number of other vitamins, minerals and nutritional supplements).

You indicated in your last post that you didn't know whether your endometrial cancer was a stage 2 or 3, but that you knew that you had a couple of positive lymph nodes. Here is a site from the American Cancer Society, which provides the endometrial cancer staging:

The ACS information states that endometrial cancer where there is lymph node involvement would be classified as stage 3C.

Best regards,

Unread 02-23-2004, 03:08 PM
Anybody using estrogen after cancer diagnosis?

Hi yellow Rose.
HRT or no HRT-what a difficult question.
I had originally opted not to have hrt and did so for five months after surgery. I'm 36 and was diagnosed with ovarian cancer at 35. I had the typical hot flashes, my skin started to get very dry, I also started to have vaginal dryness.
I met withy my gynecologist to discuss hrt. She definately wanted me on Estrogen. My oncologist had prescribed an estrogen patch in the hospital after surgery and instructed me to "use it if you have symptoms" and this was only after I asked. My gyn instructed me to use the Estridiol patch. I've since changed to the Vivelle Dot .1 mg as it is small, clear, and stays on.
My gynecologist said I am too young not to have the benefits of estrogen (cardiac, bone). It is a very confusing topic.
Unread 02-23-2004, 05:18 PM
Anybody using estrogen after cancer diagnosis?

Thank you Moekay and mojo23 for your replies. Moekay, did you cut vit E capsules and then applied the oil? How often do you use the vit E vaginally? I know eventually I have to use estrogen vaginally even if I discontinue now with estriol. I am seeing if I can postpone using estradiol for another year or so but am scared if I will end up with vaginal atrophy if I don't use estrogen.
This is definitelya difficult choice.
Unread 02-23-2004, 08:14 PM
Anybody using estrogen after cancer diagnosis?

I am 2+ mo post op TAH/BSA endo cancer stage 1. No chemo or radiation. Just f/u every 3 months. My gyn would not prescribe HRT due to my diagnosis and the fact hat my sisiter (1 months younger) was diagnosed with breast cancer and ovarian cancer one 1 months ago. I have experienced hot flashes and nite sweats, so gyn prescibed Effexcor 37.5 mg 2xs a day. It takes to curb off and I get thru te nite. Not sure how long I have to take Effecxor- will ask in April at 1st f/u. Sister also was not offered HRT- she is on the same medicine as me. We live at opposie sides of the states and have teh samemedicien-imagine that. Take the advice of your DR- the are the ones we rel on.
Unread 02-23-2004, 08:16 PM
Anybody using estrogen after cancer diagnosis?

Sister is 14 months younger and was diagnosed 14 months ago. Sorry for the typos.
Unread 02-23-2004, 08:42 PM
Anybody using estrogen after cancer diagnosis?

Hi umass07,
My hugs to you. Your family has certainly gone through a lot with two people diagnosed within such a short interval of time. Somehow uterine, ovarian and breast cancers are all interconnected. I wish you good luck with your recovery.

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