Indole 3 Carbinol

I was researching treatments for cervical dysplasia and came across a lot of information about a substance known as Indole 3 Carbinol which contains concentrated amounts of the substance found in cruciferous vegetables such as broccoli and cabbage. It sounds promising as some of the studies I was looking at showed regression of dysplasias (even the II and II categories) in about 50 percent of patients within 3 months. It looks like it is well tolerated and readily available. I wonder if any of you ladies know about this or have any thoughts about this matter. Apparently there is research about its benefits for breast, prostate, and colon cancer too.

Here is the link from when I first read about Indole 3!
Since then, I have been taking it.
It certainly can't hurt!!!

https://www.hystersisters.com/vb2/sho...threadid=58753

I've been checking into it, too. Here are a couple of interesting links:

http://www.health-marketplace.com/Indole-3-Carbinol.htm

http://ehscenter.berkeley.edu/public.../01_cram_1.pdf

s,
-Linda

Thanks! Yes, my thoughts are that it doesn't appear that it is hurting anyone and if it has the potential to help, maybe I should be taking it. I had a Leep done in February and will have my first post- Leep PAP at the end of June. The results were focal CIN I and II with the mild dysplasia focally extending to the margins. Wouldn't it be great if there were a way to totally overcome this awful HPV virus? Imagine, no more "high risk" worries that I imagine never quite go away. As long as I am imagining, how about a PAP that the dr. reads right in the office, because we all know that waiting for the results is by far the hardest part! I send my best wishes to all of you other ladies who have cancer concerns, whether it be cervical, uterine, ovarain, or breast!

I am also taking this for my CIS. However, I will caution everyone that there is some evidence that this can cause cancer (I can't remember which type - sorry). I did quite a bit of research before I started taking the supplement. I decided it was worth the risk but I just thought I share that in some cases there may be an increase in other cancers. Of course I believed that it was causing cancer in rats (so take it for what its worth). I too would love to have a miracle drug so that I don't have to worry about dysplasia again.

Yes, I have read that the supplement might have a paradoxical effect and cause other tumors. It does sound like it's a promising supplement and treatment for female precancers and cancers. I didn't see anything in the information I reviewed about what type of tumors they thought had been provoked in the rats, did you?

I'm in the process of submitting some links to the Resource Links directory here about I3C and both breast and cervical cancers. From what I've found, it appears that the rat data were about an increase in tumors in rats who were taking it and simultaneously being exposed to carcinogens, it was not spontaneous tumor development.

So, stay tuned and check back in Resource Links (both breast and cervical cancer areas) often!


-Linda

Thanks. I didn't look that closely at the research with the rats. From my experience as a scientist, rats are usually given such high doses of "medicines" that they would probably still get cancer if they received the same dose of aspirin. Like I said, I researched it and have decided it is worth the risk. I'm now taking 200mg a day to try and make sure that I don't end up with a reoccurance of CIS on my cervix.