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44cy dose radiation around vagina and surrounding tissue...ovary survival? 44cy dose radiation around vagina and surrounding tissue...ovary survival?

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Unread 05-05-2004, 02:09 PM
44cy dose radiation around vagina and surrounding tissue...ovary survival?

I saw a radiologist about my high risk feature of deep cervical stromal invasion and she is saying that I will have to have 4400 cgy of radiation to prevent a 40% chance of recurrence!!! Has anyone experienced doses that large? Mine will not be to the whole pelvis, only to the upper vagina and surrounding tissue. However, although my ovaries are transposed I understand there is a 50% chance of ovarian failure. Although my ovaries are already kind of sacked by the cisplatin and hysterectomy, I still have a sex drive. I just wanted to know if anyone else had received such a high dose of radiation or how soon menopause followed afterwards. Supposedly anything higher than 300 cGy is fatal to the ovaries unless they are transposed out of the scatter field. Even then, there is a 50% chance of failure, as I said.
-Kate (6 rounds of cisplatin/taxol, radical hysterectomy/lymph node dissection with preserved ovaries and radiation coming soon for cervical cancer stage 1A neuroendocrine)
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Unread 05-06-2004, 10:20 PM
44cy dose radiation around vagina and surrounding tissue...ovary survival?


I did not have radiation, but wanted to let you know that I will be keeping you in my thoughts and 'ers. Hopefully your ovaries have been moved far enough away from the radiation field that they will be out of harm's way. The few women I have spoken with whose ovaries were affected by radiation commented that it seemed there was a gradual onset of symptoms of menopause. Or perhaps the symptoms were there sooner but disguised themselves as side effects of radiation. Hopefully someone will be along soon to share their experiences with you.

Wishing you successful treatments with minimal side effects.

Unread 05-08-2004, 02:58 PM
44cy dose radiation around vagina and surrounding tissue...ovary survival?

Hi, Kate,

I just reviewed my radiation reports and they state that my external pelvic radiation for endometrial cancer consisted of a total of 4500cGy, given in 25 fractionated doses of 180cGy per fraction. I also had a vaginal cuff boost, the total dosage of which was 8360cGy at the tip of the cylinder.

I'm not sure how the dosage would differ for cervical cancer, but based on my personal experience at least, the dose you mentioned in your post would be in the typical range for endometrial cancer. I was thrown into surgical menopause by my radical hysterectomy anyway, so I can't answer your question about how quickly the radiation might cause you to experience the effects of menopause. I would suggest that you run that question by your radiation oncologist.

Good luck,

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Unread 05-08-2004, 08:21 PM
44cy dose radiation around vagina and surrounding tissue...ovary survival?

Yes, they typically remove the ovaries in endometrial cancer. I hope things have flowed smoothly for you since your treatments. As for me, my sex drive has returned fully now that the last chemo session has worn off which is creating false hope for the future.

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