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I crashed-estrogen drop or prog drop? I crashed-estrogen drop or prog drop?

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Unread 03-25-2001, 05:25 PM
I crashed-estrogen drop or prog drop?

I have written here how well I've done on otc progesterone cream. It pretty much alleviated the panic and anxiety I was feeling. I'd been using it for 2 months without a break. My symptoms were pretty controlled, except sore breasts from my own natural estrogen for 5 solid weeks-thought maybe estrogen dominance increased as it can when prog is first added.

I decided maybe I should take a break just as my breasts finally went back to normal. It was quite like a drug withdrawal as I could tell my estrogen plummeted. Here I was, out of town with my husband, meeting the big wigs at his new job and I crashed.

I have 2 kinds of attacks-one with the panic and high blood pressure which comes when I'm pumping the estrogen (and helped by the prog) and the other when the estrogen bottoms out and I get sensations of either hot or cold water cursing thru my whole body, get dizzy, diarrhea, vomit and feel out of this world. That second one happened to me and I had to hide out in the hotel room all day. That was the third day without any prog and I immediately started it up again. Started to feel better by the next day. But was my body just adjusting to the withdrawal of estrogen?

So, now, I don't know if the estrogen withdrawal caused the weirdness (my dr. says he thinks women can have a withdrawal type reaction with fluctuating hormones) or if it was caused by discontinuing the prog for three days. Or both, in combo. I was concerned about giving my body a prog break, but I don't think I want to try that again for a while.

Also, I had posted about high blood pressure. Tracking it, I discovered that it went down considerably when the estrogen seemed to plummet. And each time I exhibited it at the dr's office was when my breasts were sore and swollen and I could feel the prog keeping the panic where I could control it.

So, I am not sure what to do. I know this estrogen dominant thing has to end eventually, I'm 51. In the meantime, I wonder about some supplemental estrogen to get me through the big plummets (but I don't know when they're going to come, everything is so irregular now) or would that make things worse? As I've said before, keeping ovaries doesn't mean a nice menopause. I feel like I'm being thrown around like a sack of potatoes at the whim of what my system decides to do all of a sudden and there's not much control over it, except to add some progesterone to keep the panic meanies at bay.

Good grief, Charlie Brown!!!!!!!!!! I know there's so many of us trying to figure this out. Thanks, Linda
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Unread 03-25-2001, 09:42 PM
I crashed-estrogen drop or prog drop?

I totally sympathise as I have been and at times still are where you are at now. You are right in that for some of us who retained ovaries menopause can be h_ll :dragon: As you and I have both worked out it's because of that never ending, ever-changing roller coaster we find ourselves on. I have had trouble getting this far and still have a lot of issues to address and some pretty weird symptoms. Hopefully the endocrine specialist/gyn I am seeing in a couple of weeks can shed some light on my situation.
As you know we have to go on how we feel and I can only give you my advice on what has worked so far for me (and I can't remember what you have and haven't tried)!
I had huge fluctuations of estrogen for the first few months, sometimes dominence and sometimes rock bottom (vicious hot flushes and night sweats) as it all tried to sort tiself out. My pituitary gland was trying to give the signals but my ovaries were not responding. The anxiety was incredible! I tried Premarin .625 and it alleviated a lot of things but killed my sex drive and response. It also seemed to build up in my system and give me a prostaglandin problem, similar to the backache etc. before periods but 50 times worse
Went off it and tried black cohosh/vitamin/mineral supplement: slight improvement in the anxiety but not enough and the return of the dreaded vaginal irritation and hot flushes/night sweats and no sleep.
Tried a bioidentical form of estradiol (Estrafem 1mg) similar to your Estrace over there. Well it hardly made a dent and sent me into a place I never want to go back to. I nearly went to ER and asked them to lock me up and throw away the key! I think the reason for this was that it interfered enough to create a disturbance for my ovaries but not enough to stop them trying to cycle on their own. Then I was introduced to the wonderfull world of transdermal estrogen - what a relief - the roller coaster slowed to a quiet clatter for the first six weeks, I stopped ovulating and hot flushing everywhere. It was a much more even ride for me and made a real difference. Whether it worked better because ovulation stopped on it's own? Whether ovulation stopped because there was a steady constant flow of estrogen into my body which ended the negative feedback, I don't know. But I have read that for women with ovaries a transdermal method may be best - feeding something straight into the bloodstream rather than the liver chewing it up and releasing it in a big bang and then bottoming out later.
Nearly 4 months down the track I am feeling low on something - not having very sore breasts but big anxiety again, early waking, aching hips and the dreaded involuntary head jerking (even when I am relaxed!). I will see what the specialist says and hopefully with the addition of some progesterone cream I can achieve something better. I was told by a compounding pharmacist that when starting prog. cream (if and when I do) to halve my estrogen dose as it makes the estrogen receptors more sensitive - so maybe that's what happens when you take it? I was also told after 3 months of taking the progesterone cream to halve the dosage of it once it had built up in my system and reactivated the receptors even more. I haven't tried it so can't testify to this working.
I also found my breasts were more sore in the early days when I was on a bigger roller coaster. I always thought they were from too much estrogen certainly the case when I had fibroids pre-hyst but I also found my fluctuation and changing levels caused them after the hyst. I don't know if any of this applies to you or if it will help but I just wanted to offer you a big hug as I know how you feel. I hope you can find some compromise soon that will help you to feel better.

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