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Radical Hyster followed by Radiation or radiation and chemo??? Radical Hyster followed by Radiation or radiation and chemo???

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Unread 05-26-2007, 03:13 PM
Radical Hyster followed by Radiation or radiation and chemo???

I had a radical hysterechtomy 5+ weeks ago for cervical cancer. The pathology report originally stated I had a stage 1b1 adenocarcinoma tumor with poorly differentiated cells. Lymph nodes and all margins were clear and there was no lymph-vascular invasion. After the slides were reviewed a second time my cancer was restaged to 1b2. I am deciding whether or not to do radiation alone or radiation with chemo and have been given oposing positions on this.
I need help. If anyone out there has a similar case history and can offer advice/ experiences please respond.
Thank you
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Unread 05-26-2007, 10:41 PM
Radical Hyster followed by Radiation or radiation and chemo???

What made your cancer change stage? A stage 1B2 means that the tumor was larger than 4cm. Usually doctors can see that, before surgery. Normally cervical cancer is staged before surgery.

In any event, radiation plus chemo is the standard treatment for cervical cancer stage 1B2 or higher. Why are you considering omitting the chemo booster? You won't lose your hair. I had no side effects from the chemo.

What does your gyn/oncologist recommend?

Unread 05-27-2007, 06:19 AM
Radical Hyster followed by Radiation or radiation and chemo???

The cancer was staged as a 1b1 prior to the surgery and the initial pathology report also said it was a 1b1. When the radiation oncologist had the slides reviewed again to double check for any vasucalar invasion it was then restaged to a 1b2. My guess is that it was bordeline.. the cancererous area was probably less than or close to 4cm, but the actual overall tumor was larger. The radiation oncologist believes that two out the three treatments 1) radical hysterectomy with removal of the ovaries and fallopian tubes and 2) radiation is plenty for me. My OBGYN oncologist thinks that the possible risks of long term side effects of adding chemo outways the benefits and she is in agreement with just doing the radiation. In fact she indicated that she thinks that with the prophylactic dose of radiation I may very well be cured. She was very pleased with the surgery and loof of the surrounding organs and margins. Of course I may be cured without doing anything. The other oncologist I spoke with worked with my mother. She passed away from ovarian cancer two years ago. Just so you know I was adopted and I have no gentic history of cancer. (go figure) Anyway, he is from my hometown and believes in treating this as agressively as possible. Now I have to make a decision. I have a little more time to think about becuase I am waiting for my incision to heal. I developed an infection 3 days after the surgery and the incision had to be reopened. I get the wound packed and treated daily. It is still not completely closed, but healing rapidly and almost there. So by the first week of June I will be ready for radiation to start. I welcome more advice and experiences. Thanks.
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Unread 05-27-2007, 02:43 PM
Radical Hyster followed by Radiation or radiation and chemo???

Long term effects of chemo? I wasn't aware that there are any. There are long term side effects to radiation. Perhaps he meant that chemo would boost radiation and give you more radiation side effects.

Cervical cancer is caused by a virus, so heredity doesn't play any part.

Can you ask your doctor what your survival rates are, with radiation and without? I know that my doctor said that my stage 1b2 had an 80% cure rate with radiation and chemo. AFter two years that went up to 96%!

Sounds like both of your oncologists believe that radiation alone is enough. That's good!

Unread 05-27-2007, 03:31 PM
Radical Hyster followed by Radiation or radiation and chemo???

You are correct.. The chemo will increase the risks of long term side effects of the radiation when used in conjunction with it. There are also many side effects short and long term from the chemo such hearing loss and tinnitus. In fact I am very concerned about the ototoxic nature of Cisplatin since I have a significant loss of hearing already. I guess my thinking is that with the Chemo everything in your body is somewhat at risk whereas the radiation is at least focused on a specific area. I would love to hear your thoughts on this.

The survival rates that were reported to me by the radiation oncologist were 80% without doing radation and will increase to 90% with the radiation. I do not have an official number if the chemo is added. But 90% is very good in my opinion. The other oncologist reported 70-75% chance of survival with the hysterectomy alone and will increase to 85%-90% with the radio/chemo. The problem is the studies vary so much, who knows what to believe.

Thanks again for your input. Lynn
Unread 05-27-2007, 04:24 PM
Chemo longer term....

Chemo may increase one's risk of other cancers down the road, Janie.
Unread 05-27-2007, 04:52 PM
Radical Hyster followed by Radiation or radiation and chemo???

Wow. I didn't know that! What cancers might come from cisplatin boosters? I had NO idea.

Unread 05-27-2007, 05:29 PM
Radical Hyster followed by Radiation or radiation and chemo???

I need to vent.. How in the world did I end up with cervical cancer when I had normal annual PAP's all this time year after year and no history of HPV. WHY WHY WHY???? My cancer was found on top of the cervix and growing up into the uterus. A cancer located in an area unable to be detected by PAP smear testing. Given my history and symptoms it was initially thought that I had uterine fibroids. I am still in shock. I am a walking commercial a HPV vaccine commercial. Just had to get that out....
Unread 05-27-2007, 11:08 PM
Radical Hyster followed by Radiation or radiation and chemo???

Same here! I had 30 years of negative paps, no partners other than DH for over 20 years, never tested positive for HPV. I had a negative pap a few months before my first symptoms of cancer! I too was told that it was probably fibroids. Two sonograms, one by a gyno expert, thought that I had a fibroid on my cervix. My wonderful gyn insisted that I see a gyn/oncologist 'just to be sure'. One look and the gyn/onc staged me. He knew exactly what he was seeing. A biopsy confirmed it.

All I can conclude is that pap smears don't work for everyone, and **** happens. It stinks, but it does.

Sorry that you are having to deal with this.
Unread 05-28-2007, 06:48 AM
Radical Hyster followed by Radiation or radiation and chemo???

First, I am so sorry for all that you are going through and I hope that the surgery takes care of everything. I will pray for you.

But reading this thread has gotten me worried. I also had a radical hyst for cervical cancer 1B2....and I have HPV. I was told I wouldnt need radiation afterwards.

Everything came out and all nodes were clear and negative.

But I see that so many women on this site with the same diagnosis have had radiation. Now I am worried. My recuperation went well and I dont see my gyn/onc until July for the first of many 3 month checkups.

I am so confused now. I am thinking of calling my doctor tomorrow.

Does everyone with cervical cancer 1B2 need radiation after surgery?????

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