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endo and estrogen endo and estrogen

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  #1  
Unread 02-26-2008, 11:00 PM
endo and estrogen

I am 3 weeks post op and initially didn't have any menopause symptoms, even when my dr put me on estradiol 2mg after 8 days.. still no symptoms. I am concerned firstly why he put me on them without symptoms (did he do it to shut me up when I asked about it initially?) and secondly obvoiusly because of the endo/est link...I don't know where to turn for a straightforward answer.

~Sass
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  #2  
Unread 02-27-2008, 10:29 AM
endo and estrogen

Hi sassibella
They put you on HRT early due to your young age, but it is wise to look for more answers, you have endo and most MD wait a few months to start HRT to allow things to quiet down. ? second opinion/endo specialist.
  #3  
Unread 02-27-2008, 12:57 PM
endo and estrogen

Hi again (((Sass)))

Part of the problem I am having here is that your DR must be using a different definition of what is "synthetic" than is usually used. Usually "synthetic" is used to mean "non-bio-identical". That is not strictly correct, but it's the common usage. If by "synthetic" your DR means "not made by the ovaries" then yes, your estradiol is synthetic - and so is everything else you put in your body. However, the estradiol you take is the exact same molecule your ovaries made. After 95% of it is cleared in the liver when you take the pills, the remaining 5% ends up in tissues as the exact same estrogen your ovaries made. So, I am having a whole lot of trouble understanding how it would have a different effect on endo than your own ovaries' estrogen did.

If your DR is actually saying that estradiol is not the same as your ovaries' estradiol, well, that is just wrong. So I'm giving him the benefit of the doubt and assuming we are just speaking different languages.

Anyway, there is so much contradictory information out there about the effect of estrogen on endo after a hysterectomy that it makes it hard to make a decision about what to do. Also, different women have different considerations; for example, younger women have a greater need for estrogen than those of us who are closer to the age of natural menopause; and women with a lot of risk factors for female cancers have to consider the risk involved in taking synthetic progestins to balance the estrogen, which can help minimize the effect of estrogen on remaining endo implants.

In case you haven't already seen them, here are a few links with some of what is currently known about the effect of using HRT after surgery for endo:


http://www.obgyn.net/women/women.asp...icles/endo-hrt

http://books.google.com/books?id=Mak...wlo2NSlwhT1CxE

http://www.ncbi.nlm.nih.gov/sites/en...indexed=google

http://meds.queensu.ca/medicine/obgy...riosis.htm#HRT

http://books.google.com/books?id=0GW...hJa3J0mbfzQGac

and this one just has some good general information about all types of endo treatments, including HRT:

http://guidelines.endometriosis.org/pain.html

It does sound like your DR put you on HRT due to your young age; I would just question why you were not given any type of progestin, or even natural progesterone, to balance it and help minimize your risk of recurrence. If it's possible, I would suggest consulting an endometriosis specialist or endocrinologist with experience treating endo patients to ask them what is best for you.

In the end, the HRT decision comes down to a balancing of risks and benefits for all of us, and you have the risk of endo recurrence to consider along with all the other risks (bone loss, quality of life, etc). Continue to read all the info you can find on this, and you will be in the best possible position to make the right decision for you - and remember, nothing is cast in stone; you can change your mind if you start having symptoms or if new information comes out that supports a different point of view.

Good luck!
s,
-Linda
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  #4  
Unread 02-29-2008, 08:34 AM
endo and estrogen

  Quote:
Originally Posted by Sassibella
I am 3 weeks post op and initially didn't have any menopause symptoms, even when my dr put me on estradiol 2mg after 8 days.. still no symptoms. I am concerned firstly why he put me on them without symptoms (did he do it to shut me up when I asked about it initially?) and secondly obvoiusly because of the endo/est link...I don't know where to turn for a straightforward answer.

~Sass
I too was started on estrogen right away because of age, but I was told I have to take progesterone also. It opposes the estrogen and prevents the spread of endo which I had been dealing with for years. You may want to ask for a form of progesterone. In my case I prefer the synthetic progestin over the bio identical one. I seem to have less mood issues with it. You will have to try different things and see what is best for you. I would recommend a specialist in endo though. Most pelvic pain clinics have doctors that are experts. They can help you keep your endo at bay. I hope you get some straight answers. I know surferbabe knows what she is talking about. Good luck.
Janelle
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