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BRCA2 mutation BRCA2 mutation

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Unread 03-23-2008, 09:21 PM
BRCA2 mutation

Have any of you sisters been diagnosed with the BRCA2 mutation? What procedures have you had, been recommended or contemplating? I have recently been diagnosed and would like to chat with others with the same diagnosis. I would enjoy hearing from anyone with information.....
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Unread 03-24-2008, 11:05 AM
BRCA2 mutation

Hi there!
I'm sorry you have these worries!

What is your diagnosis? Our cancer concerns forum may be just the place for you to find more info regarding your BRCA testing questions. Check us out at

Good luck, and please give us more information so that we can help you!

Unread 03-24-2008, 07:00 PM
brca2 mutation response

With the mutation I have there is up to an 87% chance of breast cancer and up to 27% chance of getting ovarian cancer. Highly recommend complete hysterectomy since ovarian cancer is usually diagnosed in later stages. Want me to do the tamoxifin or other drug(forget name) to reduce risk of breast cancer if I do not have a double masectomy. Inherited genes can make a person think.....I hate surgery, but I hate the thought of cancer even more. I am scheduled for a hysterectomy on 5/20/08, hope there is no sign of cancer when all is removed. Was wondering if anyone else in this great group has an experience with gene mutation diagnosis.
This is a great site, glad I found it. I have read alot of good ideas to help with my trip to castle.
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Unread 03-24-2008, 07:38 PM
BRCA2 mutation

I have a strong history of breast cancer in my family, along with some ovarian. After my younger sister had breast cancer, all of my other sisters were able to have BRCA1 and BRCA2 testing done. Out of the six tested, only one had the gene mutation. Since her findings, she has had a double mastectomey and a total hysterctomy as a preventative measure.

Something interesting - My mother passed away (61y/o breast cancer) and my aunt, her sister (58 y/o ovarian cancer). There was another sister to my mom who had gone and had all breast tissue removed and implants put in years before the others had their cancers. I think that it was more of a cosmetic thing for her. She also eventually had a hysterectomy. She is still living, never had cancer, and is in her 70s. Since her two daughters had both had cancer (one ovarian and one breast), after all my sisters and I had our BRCA testing done, she did too. She found out that she has the gene mutation. I just think that is rather interesting. I think this is what promted my one sister who has the mutation to have her two surgeries done.

I know that I've rambled here, but maybe this will help you in some way.
Unread 03-24-2008, 08:09 PM
BRCA2 mutation

Thank you very much for your response. I am having a TAH/BSO in two months. Will be so glad when it is over, won't worry about ovarian cancer then. But, I am less focused on both breast removed....for now, going to take tamoxifin to reduce risk. When I really think about it I flirt with the idea of masectomy. My Mom had breast cancer 8 years ago and has had constant pain ever since operation, they nicked a nerve. Her sister also had breast cancer, three times in on breast. My Dad's only sister died of ovarian cancer and her daughter was diagnosed with ovarian cancer at same age as her mother died. She was also diagnosed with breast cancer a few years later. So I really do have a history of cancer in my family. Decisions, hard to decide. Don't want to over react, but want to be cautious.
Look forward to hearing from other Hyster Sisters.
Thanks for your input, food for thought.

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