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08-03-2010, 07:26 PM
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Posts: 30,771
Hysterectomy: February 4th, 2002
Surgery Type: TVH
Ovaries: Removed both
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Re: HRT linked to cancer? Doc says no
Hi Loracann  Well, according to the WHI study data, once they were properly analyzed, it appears that the Provera component of the combination HRT Prempro is associated with a slight increase in breast cancer rates. However, women on estrogen-only HRT had no increase in breast cancer rates; in addition, those women in the study who got breast cancer and were on HRT had much better survival rates than women who were not on HRT and got breast cancer. So, despite a history of breast cancer myself, I'll take my chances on estrogen-only HRT, which also protects my bones and cardiovascular system. My DR agrees.
And, yes, your ovaries made more estrogen than you get in HRT. In addition, while the types of estrogen we use in HRTs do not cause breast cancer, there is a metabolite of the weak estrogen called estrone which can cause tumors (at least in rats). Menopausal women who have their ovaries tend to make more estrone; therefore, their breast cancer rates are higher than women without ovaries (on HRT or not).
I hope this helps!
 s,
-Linda
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