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Anyone use Activella? Anyone use Activella?

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Unread 01-12-2012, 05:19 PM
Anyone use Activella?

I have been horribly worried about the HRT. I'm post-op 2 weeks today; had ovaries, uterus and part of the cervix removed because of endometriosis. My doctor told me yesterday that I should not take black cohosh because it works like estrogen. Anyone that has endo doesn't need that because it can cause the endo to reactivate. He said they are trying to phase out Premarin. Not sure what that means. He said I need a dual working HRT. He put me on Activella. Has anyone used it? I'm looking for testimonials on Activella. I have it sitting beside of me and I'm so afraid to take it. What time of the day should I take it, when I work up the nerve to?
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Unread 01-12-2012, 06:17 PM
Re: Anyone use Activella?

Hi I'm not sure what your DR meant when he said they (Wyeth?) are trying to phase out Premarin, but Premarin is alive and well and shows no signs of dying any time soon.

Activella is a combination HRT taken orally; you can get the same combination in transdermal form as brand name Combipatch. So, if you are concerned about exposing your liver to the larger doses of hormones necessary when they're taken orally, you might ask your DR if Combipatch is an option for you.

As far as the Activella goes, I have not taken it (no endo history) but if you do a search here you'll find some women who have. It doesn't matter what time of day you take it as long as you take it at the same time every day. Most women take it in the morning, finding it easier to remember then. Just don't take it with breakfast if you drink grapefruit juice, as there is an interaction between them which causes you to have higher estrogen levels than you ordinarily would.

I hope this helps.

Unread 01-15-2013, 11:02 PM
Re: Anyone use Activella?

I have been on it for four weeks now. I am starting to question it. I have no night sweats, no hot flashes but I have become very anxious with major mood swings a little bit of depression and now headaches are beginning. I'm beginning to wonder if this is actually side effects of the drug and not menopausal symptoms. However, I have no idea what my menopausal symptoms would be without being on HRT. I started on Activella the day after I had my surgery. I'm now questioning if I should've waited to see what my symptoms would've been like without it.

All our bodies are different you might just be fine it. Many people are.
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Unread 01-16-2013, 10:36 AM
Smile - Anyone use Activella? Re: Anyone use Activella?

Flyingmonkey: I experienced the same symptoms you mentioned when I went off of Activella. My hubby was laid off from his job and we lost insurance. I asked my doc to give me something that was similar to it, but cheaper. He put me on Prempro. It almost drove me insane!!! I was so angry all the time and even had thoughts of killing my husband. I begged to go back to Activella and cut monthly expenses so we could afford it. It has helped me so much!! No hot flashes, night sweats.....lessened mood swings.

I would suggest you either research hrts that ladies on here have had success with and then talk with your doc. I am so sorry that it's not working for you. I've been on it, mainly, for a year now and it's been a God send. My hyster was 12/29/11. I am still worried about the comment on the literature that you are not suppose to be on it for more than a year if you do not have a uterus. I predict a conversation with my doc in the near future.

Keep me posted on how you do. If you need to talk, I'll be here for you!
Unread 01-17-2013, 08:00 AM
Re: Anyone use Activella?

Petunia, thank you for letting me know that I'm not going insane.

I go to my doctor today and it will be a long conversation on this. Because what I'm noticing is my symptoms are getting worse the longer I'm on this drug. I'm wondering if I'm actually reacting to the progestin and not the estradiol in it. I'm supersensitive to Preservatives and a synthetic drug may be a problem.

All I know for sure is I can't live like this and I can't work like this and it's making me regret the surgery. It's no fun standing on the edge of an abyss every single day.

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