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MTHFR (Methylenetetrahydrofolate reductase) mutation?? MTHFR (Methylenetetrahydrofolate reductase) mutation??

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Unread 06-11-2014, 10:17 AM
MTHFR (Methylenetetrahydrofolate reductase) mutation??

Hoping to find someone with knowledge of MTHFR mutation- I've had both ovaries out and I'm bring told I can't have Hormone replacement/ estrogen due to mutation and risk for blood clots.
Any advice out there??
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Unread 06-15-2014, 08:03 PM
Re: MTHFR mutation??

I have this mutation too (both strands). I haven’t found many doctors who even show interest in it.
Unread 06-16-2014, 05:54 AM
Re: MTHFR mutation??

Thank you so much!
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Unread 06-18-2014, 01:10 AM
Re: MTHFR mutation??

Here are a couple links that may help: NIH MTHFR info and MTHFR Awareness Site. I hope you get it figured out.
Unread 06-18-2014, 06:24 AM
Re: MTHFR mutation??

Thank you so much for the information. I'm studying every word.
Unread 06-18-2014, 03:36 PM
Re: MTHFR mutation??

Here's one more. It's one of the articles very recently added to this site. MTHFR mutation 101.
Unread 06-19-2014, 09:02 PM
Re: MTHFR (Methylenetetrahydrofolate reductase) mutation??

Are you being told that you cannot have HRT _because_ of your MTHFR mutation/s? I'm very interested - I'm wrestling with the ovary decision. I'm double trouble on the 677 mutation but I'm okay on 1298

EDIT: found the following research that indicates that the bad version of 677, especially the doubly-bad 677TT, is actually _protective_ against breast cancer when on HRT. Maybe something to share with your doctor?

...These findings suggest that the MTHFR 677TT genotype may confer a 40% decreased breast cancer risk in postmenopausal women using HRT...
That said, I haven't found anything on the clotting issue yet.
Unread 09-10-2014, 01:38 PM
Re: MTHFR (Methylenetetrahydrofolate reductase) mutation??

I have MTHFR Too
Unread 10-09-2014, 03:00 AM
Re: MTHFR (Methylenetetrahydrofolate reductase) mutation??

Another, er? Here! I find that the enzymatic B vitamins have been great for me (not good at breaking those down). Also, I don't convert beta-carotene to A almost at all and that's also related somehow. I have to take a regular vitamin A suppl ands that's been helpful.
Unread 11-17-2014, 04:26 PM
Re: MTHFR (Methylenetetrahydrofolate reductase) mutation??

I have that too. Isn't that the funniest acronym EVER? In all seriousness, I used to work in a coagulation dept of a lab and asked our specialist about it. He said it really wasn't that big of a deal. Whatever that means.

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