MTHFR (Methylenetetrahydrofolate reductase) mutation??

Hoping to find someone with knowledge of MTHFR mutation- I've had both ovaries out and I'm bring told I can't have Hormone replacement/ estrogen due to mutation and risk for blood clots.
Any advice out there??

I have this mutation too (both strands). I haven’t found many doctors who even show interest in it.

Thank you so much!

Here are a couple links that may help: NIH MTHFR info and MTHFR Awareness Site. I hope you get it figured out.

Thank you so much for the information. I'm studying every word.
Bonnie

Here's one more. It's one of the articles very recently added to this site. MTHFR mutation 101.

Are you being told that you cannot have HRT _because_ of your MTHFR mutation/s? I'm very interested - I'm wrestling with the ovary decision. I'm double trouble on the 677 mutation but I'm okay on 1298

EDIT: found the following research that indicates that the bad version of 677, especially the doubly-bad 677TT, is actually _protective_ against breast cancer when on HRT. Maybe something to share with your doctor? http://www.ncbi.nlm.nih.gov/pubmed/15598763

	Quote:
...These findings suggest that the MTHFR 677TT genotype may confer a 40% decreased breast cancer risk in postmenopausal women using HRT...

That said, I haven't found anything on the clotting issue yet.

I have MTHFR Too

Another MTHFR...um, er? Here! I find that the enzymatic B vitamins have been great for me (not good at breaking those down). Also, I don't convert beta-carotene to A almost at all and that's also related somehow. I have to take a regular vitamin A suppl ands that's been helpful.

I have that too. Isn't that the funniest acronym EVER? In all seriousness, I used to work in a coagulation dept of a lab and asked our specialist about it. He said it really wasn't that big of a deal. Whatever that means.