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Important news article re:  OC Important news article re: OC

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Unread 08-28-2002, 08:39 AM
Important news article re: OC

I found this at MD makes for very interesting reading

NEW YORK (Reuters Health) - Greater support from friends and neighbors of presurgical patients with ovarian carcinoma appears to be associated with reduced level of vascular endothelial growth factor (VEGF) and possibly less disease progression, according to researchers at the University of Iowa, Iowa City.

Lead author Dr. Susan K. Lutgendorf told Reuters Health that much research on relationships between psychological factors and cancer has concentrated on the immune system. "The exciting thing about these findings is that they open up the possibility of a new mechanism by which psychological factors may be related to cancer progression--that is, through effects on factors related to angiogenesis."

Dr. Lutgendorf and colleagues note that VEGF is modulated by a variety of behaviorally sensitive factors. This "key" cytokine can stimulate tumor angiogenesis in patients with ovarian cancer and is associated with reduced survival.

To determine whether social support, depressive symptoms and VEGF levels might be related, the researchers surveyed 24 preoperative patients with ovarian carcinoma and another 5 women with benign pelvic masses. The findings appeared in the August 15th issue of Cancer.

The women with carcinoma who reported higher levels of social well-being had lower levels of VEGF. Greater support from friends and neighbors and less distance from friends were among factors associated with lower VEGF levels.

Subjects who reported greater helplessness or worthlessness had higher VEGF levels, but, say the researchers, "depression as a whole...was not related to VEGF levels."

The investigators concede that the study had a number of limitations, but conclude that the results "point to the possibility of novel pathways between biobehavioral factors and tumor angiogenesis." And, said Dr. Lutgendorf, "these findings open up a new area of research into mechanisms underlying these relationships."

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Unread 08-29-2002, 07:07 AM
Important news article re: OC

thanks for that article, tess. i'm reading a book now by bill moyers titled, "healing and the mind." one of the chapters talks about the value of touching, hugging, etc. just like the study with premmie newborns, they need human touch to get stronger and thrive, feeling close and connected with loved ones has physical benefits. if you feel better, emotionally, chances are your body can work better and help in combating illness more effectively.

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