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Can Non-Invasive change...... ? Can Non-Invasive change...... ?

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Unread 11-04-2002, 08:42 AM
Can Non-Invasive change...... ?

Can Non-invasive implants turn into invasive implants

also if my lymph nodes and blood stream dont show any malignancy..... can it show malignancy later on?

i was initially diangosed with a Borderline Ovarian Tumor, had my TAH/BSO and the peritoneal lesions ( 2 of them) came back with borderline serous tumor implants

as above, its not in my blood stream or my lymph nodes and i have been told there is no way of knowing if it spreads, but im just curious about the above questions

any input would be helpful

(p.s. karenann, ive checked out the john hopkins site u showed me and it answered my question on the other thread, but i didnt see anything about this, if maybe u can find a section on that site for me)
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Unread 11-04-2002, 10:33 AM
Can Non-Invasive change...... ?

This is from the hospkins website (APSTs are atypical proliferative "borderline" serous tumors:

The disease specific survival rate of patients with APSTs confined to the ovaries, or with microinvasion or even with lymph node involvement approaches 100%. The behavior of APSTs with extraovarian disease is based on the type of implants that are present. The survivial rate of patients with APSTs with non-invasive implants is 95-100% after a mean follow-up of 7.4 years. In general, the non-invasive serous tumors associated with invasive implants are micropapillary serous carcinomas, not APSTS
My understanding, is that most borderlines have an "indolent" course, except the MPSCs which seem to cause more trouble and re-occur more often.

If you have any doubts, get a second opinion. I had three pathology opinions before I was absolutely sure of my diagnosis and its implications. I made my gyn onc and pathologist go over every line of my report with me, in person. I think they thought I was a bit nuts. Better that than sitting around confused and worried.

Unread 11-04-2002, 06:01 PM
Can Non-Invasive change...... ?

s Ksses

There are no perfect guarantees in life. And sure there is always a small chance things could change. But your prognosis sounds positively positive to me. In addition to Dorrie's great info above, here is another web site you and your hubby might enjoy reading. It is from the National Cancer Institute.
Best wishes and keep in touch.

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Unread 11-04-2002, 08:12 PM
Can Non-Invasive change...... ?

Thanks karenann and DorrieL

so far ive been told by a couple of people to get a second opinion just because they didnt like the sound of "there's know way of knowing if it spreads" and my DH wants it all out of me, he is worried about the fact that their is still borderline cells still inside me

me? ive been able to understand that since its not int he blood stream and lymph nodes that it, nothing else needs to be done

im not looking foward to having to go thru anything else at all especially after this hyst ugh !
Unread 11-05-2002, 06:20 AM
Can Non-Invasive change...... ?

For a second pathology opinion - nothing is done to you. The hospital sends a sample of the tissue that is removed to another pathologist.

Usually for suspected ovca, the gyn onc samples tissue all over your abdominal cavity. When a second opinion is obtained the second pathologist looks at a piece of each tissue. Because there are so many types of ovarian tumors, it is not at all uncommon to get a second opinion on the pathology.

You might want to look at the operative report - reading the doctor say I checked this and it was normal, I sampled this, that and the other and it was normal can be very reassuring.

I would suggest that you and your husband sit down with your gyn oncologist and ask as many questions as you need to -- until you are both confident in the information.

Unread 11-05-2002, 04:53 PM
Can Non-Invasive change...... ?

s ksses

Here is a link to the spot on the Hopkins web site where it discusses second opinions on borderline tumor pathology slides. Like Dorrie said, you need not even be present. Get your gyn onc to send your slides to them.

Hope this helps. And it might actually be a good idea.


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